DFBE-95【79089-72-8】Precursor for [11C]Flumazenil
DFBE-95
79089-72-8
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Specification

Product Name: Desmethylflumazenil
Synonyms: 4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, 8-fluoro-5,6-dihydro-6-oxo-,ethyl ester, 8-Fluoro-5,6-dihydro-6-oxo- 4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester; Desmethylflumazenil; Desmethyl-FMZ; Ro 15-5528
CAS No.: 79089-72-8
Molecular Formula: C14H12FN3O3
Molecular weight: 289.26
Structure:
Application: Precursor for [11C]Flumazenil
Precursor for 5-[18F]Flumazenil ([18F]FEF)
Presentation: Packaged in amber vial or amber screw cap vials with teflon-coated stoppers under argon atmosphere.

  • Store the product at -20℃ and protected from light. Short term storage at higher temperatures does not affect product quality.


DFBE-95-0001x       1mg per vial
DFBE-95-0005x       5mg per vial
note: x includes A B C and D, A refers to 2ml vial; B refers to 4.5ml vial; C refers to 8ml vial; D refers to 30ml vial
*Customized dispensing is available

  • Nagren K. et al. Methylation of amide and thiol functions with [11C]methyl triflate, as exemplified by [11C]NMSP, [11C]flumazenil and [11C]methionine. J. Labelled Compd. Radiopharm. 1998, 41, 831-841.

  • Maziere M. et al. Synthesis of Ethyl-8-fluoro-5,6-dihydro-5-[11C]methyl-6-oxo-4H- imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate (RO 15.1788-11C): A Specific Radioligand for the In Vivo Study of Central Benzodiazepine Receptors by Positron Emission Tomography. Int. J. Appl. Radiat. Isot. 1984, 35, 973-976.