FBE-97【78755-81-4】Reference standard for [11C]Flumazenil
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Product Name: Flumazenil
Synonyms: 8-Fluoro-5,6-dihydro-5-methyl-6-oxo-4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester; Flumazenil; FMZ; Ro 15-1788
CAS No.: 78755-81-4
Molecular Formula: C15H14FN3O3
Molecular weight: 303.29
Application: Reference standard for [11C]Flumazenil
Reference standard for 5-[18F]Flumazenil ([18F]FEF)
Presentation: Packaged in amber vial or amber screw cap vials with teflon-coated stoppers under argon atmosphere.

  • Store the product at -20℃ and protected from light. Short term storage at higher temperatures does not affect product quality.

FBE-99-0005x       5mg per vial
FBE-99-0010x       10mg per vial
note: x includes A B C and D, A refers to 2ml vial; B refers to 4.5ml vial; C refers to 8ml vial; D refers to 30ml vial
*Customized dispensing is available

  • Nagren K. et al. Methylation of amide and thiol functions with [11C]methyl triflate, as exemplified by [11C]NMSP, [11C]flumazenil and [11C]methionine. J. Labelled Compd. Radiopharm. 1998, 41, 831-841.

  • Suzuki K. et al. Computer-Controlled Large Scale Production of High Specific Activity [11C]Ro 15-1788 for PET Studies of Benzodiazepine Receptors. Int. J. Appl. Radiat. Isot. 1985, 36, 971-976.

  • Maziere M. et al. Synthesis of Ethyl-8-fluoro-5,6-dihydro-5-[11C]methyl-6-oxo-4H- imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate (RO 15.1788-11C): A Specific Radioligand for the In Vivo Study of Central Benzodiazepine Receptors by Positron Emission Tomography. Int. J. Appl. Radiat. Isot. 1984, 35, 973-976.